Regenerating the Heart

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Medical research made huge strides in treating heart disease in the 20thcentury, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield.<p><i>Regeneratingthe Heart: Stem Cells and the Cardiovascular System </i>organizes the fieldinto a digestible body of knowledge. Its four sections cover mechanicalregeneration, electrical regeneration, cardiac tissues and <i>in vivo</i> stem celltherapies. An array of talented researchers share the fruits of their labors,with chapters covering such crucial issues as the cardiogenic potential ofvarying stem cell types, the ways in which they might be used to tacklearrhythmias, their possible application to biological replacements for cardiactissues such as valves, and the varying approaches used in the <i>in vivo</i>evaluation of stem cell therapies, including methods of delivering stem cellsto the myocardium.</p><p>Thiscomprehensive survey of an area of research with such exciting potential is aninvaluable resource both for veteran stem cell researchers who need to monitorfresh developments, and for newly minted investigators seeking inspirationalexamples.</p>