Proceedings of the Second Symposium Lyon, France, June 27-30, 1983

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Frontmatter -- PREFACE -- CONTENTS -- SECTION I. THE INFLAMMATORY RESPONSE AND ACUTE PHASE REACTANT PROTEINS -- INDUCTION AND CONTROL OF ACUTE PHASE REACTANT SYNTHESIS -- USE OF IMMUNOMORPHOLOGICAL METHODS AND HEMOLYTIC PLAQUE TESTS TO INVESTIGATE THE SYNTHESIS AND SECRETION OF PLASMA PROTEINS BY THE LIVER CELLS DURING THE ACUTE INFLAMMATORY REACTION -- PROGRESS IN PLASMA PROTEINS: RECENT FINDINGS ON THE STRUCTURE OF CERULOPLASMIN -- RECENT FINDINGS ON THE ISOELECTRIC POINTS OF HUMAN C-REACTIVE PROTEIN -- SAA IS A MORE SENSITIVE MARKER FOR CHRONIC INFLAMMATORY DISEASE THAN C-REACTIVE PROTEIN OR cti-ACID GLYCOPROTEIN -- ELASTASE-c^PROTEINASE INHIBITOR COMPLEX (E-C^PI) AND C-REACTIVE PROTEIN (CRP): EARLY INDICATORS OF INFLAMMATORY PROCESSES -- THE SYSTEM OF KALLIKREIN-KININOGENS-KININS (KKK) AND THE ACUTE-PHASE REACTANT PROTEINS (APRP) IN HUMANS UNDERGOING EXTRACORPOREAL CIRCULATION (ECC) -- EFFECT OF NON STEROIDAL ANTI-INFLAMMATORY DRUG (NIFLUMIQUE ACIDE) ON ACUTE PHASE PROTEIN RESPONSE -- TRANSCORTIN ACTIVITIES, CORTISOL AND PROGESTERONE IN PATHOLOGICAL SERA : INFLAMMATION, SEPTIC SHOCK, RENAL AND CARDIAC DISEASES -- MEASURFMENT OFHUMAN HIGH MOLECULAR WEIGHT K I M N O G E N (HMW-K) BY L A S E R NEPHELOMETRY -- SECTION II. BIOLOGICAL ROLES OF ACUTE PHASE REACTANT PROTEINS -- FUNCTIONS OF ACUTE PHASE PROTEINS IN THE INFLAMMATORY RESPONSE -- INTERACTION OF THE ACUTE PHASE REACTANTS O^-ACID GLYCOPROTEIN, C-REACTIVE PROTEIN AND SERUM AMYLOID P-COMPONENT WITH PLATELETS AND THE COAGULATION SYSTEM -- MONOCLONAL ANTIBODIES AS PROBES OF COMPLEMENT FUNCTION -- MODULATION OF FORMATION OF THE C3 AMPLIFICATION CONVERTASE OF HUMAN COMPLEMENT BY ACUTE PHASE PROTEINS -- MATERNO-TROPHOBLASTIC RELATIONSHIP IN NORMAL HUMAN PREGNANCY AND RECURRENT SPONTANEOUS ABORTION -- CHEMOTACTIC FACTORS IN THE AIRSPACES THAT MAY MODULATE INFLAMMATION -- SECTION III. PROTEASE ANTI-PROTEASE INTERACTIONS AND LUNG DISEASES -- HUMAN a1-ANTICHYMOTRYPSIN : PURIFICATION, PROPERTIES AND REACTIONS WITH SOME SERINE PROTEASES -- ALPHA1-MTITRYPSIN-PROTEASE INTERACTIONS: THE BIOLOGICAL ASPECT -- ON THE INTERACTION BETWEEN HUMAN LIVER CATHEPSIN L AND THE TWO CYSTEINE PROTEINASES INHIBITORS PRESENT IN HUMAN SERUM -- MODULATION OF HUMAN LYMPHOCYTE RESPONSES BY a i ANTITRYPSIN AND a2 MACROGLOBULIN -- MEDIATORS OF INFLAMMATION IN INFLAMMATORY ALVEOLITIS -- IDIOPATHIC PULMONARY FIBROSIS. MULTIPARAMETRIC EVALUATION OF ALVEOLAR LYMPHOCYTE AND MACROPHAGE ACTIVATION -- THE ALPHA1 PROTEINASE INHIBITOR OF THE LOWER RESPIRATORY TRACT. EFFECT OF CIGARETTE SMOKING -- COLLAGENOLYTIC ENZYMES AND FIBROSIS OF THE LUNG -- ELASTOLYTIC ACTIVITIES AND PROTEINASE INHIBITORS IN SPUTUM FROM PATIENTS WITH CYSTIC FIBROSIS -- SERUM DERIVED PROTEINS AND ANTIBACTERIAL PROTEINS IN CYSTIC FIBROSIS SPUTUM -- ALVEOLAR FIBRONECTIN AND INTERSTITIAL LUNG DISEASES -- SARCOIDOSIS : IgG, ß2 MICROGLOBULIN AND EVOLUTIVITY -- α1-PROTEINASE INHIBITOR IN MECONIUM FROM HEALTHY INFANTS AND INFANTS WITH CYSTIC FIBROSIS -- QUALITATIVE ANALYSIS OF PROTEINS OF ALVEOLAR FLUID -- PROTEASE-ANTIPROTEASE IMBALANCE IN LUNG DISEASE -- SECTION IV. INFLAMMATION AND ARTICULAR DISEASES -- THE ACUTE PHASE RESPONSE IN CONNECTIVE TISSUE DISEASE -- THE GLA-CONTAINING PROTEIN OF BONE -- ROLE OF AN ACUTE PHASE REACTANT, RETROVIRAL gp70, IN MURINE SLE -- STUDY OF 8 MARKER PROTEINS OF INFLAMMATION IN SYNOVIAL FLUID AND SERUM OF PATIENTS WITH JOINT DISEASES -- FIBRONECTIN IN ARTHROPATHIES -- SECTION V. INFLAMMATORY DISEASES OF NERVOUS SYSTEM -- MULTIPLE SCLEROSIS: CLUES FOR ITS PATHOGENESIS -- IMMUNOGLOBULINS IN NEUROPATHOLOGY -- CELLULAR INFLAMMATORY RESPONSE IN CEREBROSPINAL FLUID -- EVALUATION OF CSF LYMPHOCYTE SUBSETS USING THE OKT SERIES OF MONOCLONAL ANTIBODIES (OKT3 + , OKT4+ , 0KT8 + ) IN VARIOUS NEUROLOGICAL DISEASES -- CYTOLOGICAL STUDY AND PROTEIN PROFILE IN CEREBROSPINAL FLUID, BEFORE AND DURING TREATMENT OF NEUROSYPHILIS -- CEREBROSPINAL FLUID CYTOLOGY AND PROTEIN PARAMETERS IN 219 MULTIPLE SLCEROSIS -- INTERPRETATION OF THE PROTEIN PROFILE OF CEREBROSPINAL FLUID IN CHILDREN -- CEREBROSPINAL FLUID FERRITIN : INTEREST AS BIOLOGICAL MARKER OF CENTRAL NERVOUS SYSTEM TUMORS -- CLINICAL RELEVANCE OF BETA 2 MICROGLOBULIN LEVELS OF THE CEREBROSPINAL FLUID IN CHILDREN WITH ACUTE ENCEPHALITIS -- ELECTROPHORETICAL PATTERNS OF ACETYLCHOLINESTERASE IN CEREBROSPINAL FLUID -- CHOLINESTERASE ISOENZYMES OF CEREBROSPINAL FLUID AND GUILLAIN-BARRE SYNDROME -- LYMPHOCYTOTOXIC AND MONOCYTOTOXIC ANTIBODIES IN MULTIPLE SCLEROSIS -- INTEREST OF A HIGH RESOLUTION AGAROSE GEL ELECTROPHORESIS SYSTEM (PANAGELR) WITH A SILVER STAINING REVELATION IN THE STUDY OF CEREBROSPINAL FLUID (C. S. F.) IMMUNOGLOBULIN G -- TWO DIMENSIONAL ELECTROPHORESIS OF CSF PROTEINS : ELECTROPHORESIS QUALITY CONTROL -- SECTION VI. INFLAMMATION AND MALNUTRITION -- ANTHROPOMETRIC AND BIOLOGICAL CHARACTERIZATION OF MALNUTRITION STATES IN MAN -- NEW FINDINGS ON THE ROLE OF ZINC AS A BIOLOGICAL RESPONSE MODIFIER -- IMMUNODEFICIENCY IN PROTEIN OR VITAMIN A DEPRIVED MICE -- IMMUNOLOGICAL CONSEQUENCES OF PROTEIN DEPRIVATION IN PRIMATES -- SERUM THYMIC FACTOR (FTS) CONTENTS OF THE THYMUS IN UNDERNOURISHED SENEGALESE CHILDREN -- THE CLINICO-PATHOLOGICAL CONSEQUENCES OF SEVERE PROTEIN-ENERGY MALNUTRITION IN DECEASED SENEGALESE CHILDREN -- PROTEIN PROFILE AND THYMIC FUNCTION IN PROTEIN-ENERGY MALNUTRITION WITHOUT SURIMPOSED INFECTIONS : ANOREXIA NERVOSA -- MALNUTRITION IN CANCER AND CACHECTIC PATIENTS -- MARKER PROTEINS OF INFLAMMATION AND NUTRITION IN ADVANCED CANCER -- NUTRITIONAL AND INFLAMMATORY STATUS IN 26 CASES OF MALIGNANT HEMOP ATHIES OF THE INFANCY -- COMPARISON BETWEEN CRP SERUM VALUES AND HEMATOLOGICAL PARAMETERS FOR DIAGNOSIS AND THERAPEUTIC SURVEILLANCE OF NEONATAL INFECTION -- CONTRIBUTION OF PRINCIPAL COMPONENTS ANALYSIS TO THE STUDY OF INFLAMMATORY AND NUTRITIONAL STATUS ON INTENSIVE CARE PATIENTS -- EFFECTS OF NUTRITION ON THE POST-OPERATIVE SERUM LEVELS OF PREALBUMIN (PA), TRANSFERRIN (T) AND FIBRONECTIN (FN). -- SURGERY INDUCED MODIFICATIONS OF PLASMA PROTEINS LEVELS -- STUDY OF 8 PLASMA PROTEINS DURING A CASE OF SEVERE HEAT STROKE -- SERUM PROTEIN PROFILE EVOLUTION AFTER SUB-TOTAL HEPATECTOMY -- MALNUTRITION AND IMMUNITY IN CHRONIC HEAVY DRINKERS WITH AND WITHOUT CIRRHOSIS -- BIOLOGICAL NUTRITIONAL MARKERS WHICH POORLY REFLECT THE ACTIVITY OF CROHN'S DISEASE -- PREDICTION OF SUCCESS OR FAILURE OF PARENTERAL ALIMENTATION IN THE TREATMENT OF SEVERE FORMS OF CROHN'S DISEASE AND RECTOCOLITIS -- ALBUMIN ASSAY WITH ASTRA 8 BY A TECHNIC USING BROMOCRESOL GREEN : QUALITY CRITERIA, COMPARISON WITH NEPHELEMETRY -- QUANTITATIVE ESTIMATE OF THE NUTRITIONAL STATUS THROUGH THE MEASUREMENT OF THE ELECTRICAL BODY IMPEDENCE -- SECTION VII. MARKER PROTEINS IN EXPERIMENTAL MODELS OF INFLAMMATION -- CHARACTERIZATION OF CIRCULATING 04-ACID GLYCOPROTEIN IN NORMAL AND INFLAMMATORY MICE -- THE INFLAMMATORY REACTION OF THE DEVELOPING RAT : RESPONSES OF SERUM STEROID HORMONES AND PROTEINS -- THE EFFECTS OF ETHINYL_OESTRADIOL AND OF ACUTE INFLAMMATION ON THE PLASMA LEVEL OF RAT ALPHA-1"ACID GLYCOPROTEIN AND ON THE CELL'FREE TRANSLATION OF ITS HEPATIC mRNA -- EVIDENCE FOR THE IDENTITY BETWEEN α1-CYSTEINE-PROTEINASE-INHIBITOR AND α1-ACUTE-PHASE GLOBULIN IN RAT SERUM -- CHANGES IN CONCENTRATION OF FIVE RAT SERUM PROTEINASE-INHIBITORS DURING EXPERIMENTAL DIABETES. POSSIBLE RELEVANCE TO NON ENZYMATIC GLYCOSYLATION -- ACUTE PHASE REACTANTS, THROMBOXANE AND PROSTACYCLIN DURING CALCIUM PYROPHOSPHATE-INDUCED PLEURISY IN THE RAT -- STUDY OF THE GLYCOSYLATED VARIANTS OF CHICKEN HAPTOGLOBIN -- EVIDENCE FOR THE PRESENCE IN CHICKEN PLASMA OF A LIGAND FOR HAPTOGLOBIN WHICH DIFFERS FROM HEMOGLOBIN -- EFFECT OF AN ACUTE INFLAMMATORY REACTION ON THE HAPTOGLOBIN, ALBUMIN, CYTOCHROME P-450 CONTENTS AND GLUCOSE-6-PHOSPHATASE ACTIVITY IN HEPATIC MICROSOMAL FRACTIONS IN THE RAT -- CIRCADIAN VARIATION IN PMN—MIGRATION INDUCED BY LIVE BCG IN SWISS MICE -- SECTION VIII. LECTINS -- INTRODUCTIVE NOTES -- PART 1. LECTINS AS TOOLS -- THE USE OF LECTINS TO STUDY CHANGES IN RAT PLATELET MEMBRANE GLYCOPROTEINS INDUCED BY ORAL CONTRACEPTIVES -- IDENTIFICATION OF CYTOPLASMIC AND MEMBRANE PLATELET GLYCOPROTEINS USING A COMBINATION OF SDS - POLYACRYLAMIDE GEL ELECTROPHORESIS AND 125I-LABELLED LECTINS -- CHARACTERIZATION OF HUMAN EPIDERMAL GLYCOPROTEINS RECOGNIZED BY THE LECTINS CON A AND PNA -- FLUORESCENT LECTINS AND QUANTITATIVE MICROSCOPY -- EFFECTS OF SERUM ON LECTIN-INDUCED LYMPHOCYTE PROLIFERATION -- CONCANAVAI.IN A AND PROTHROMBIN COMPLEX -- MODIFICATION OF THYMIDINE TRANSPORT IN LECTIN-STIMULATED LYMPHOCYTES -- INDUCTION OF A THYMIDINE METABOLISME ENZYME IN HUMAN LYMPHOCYTES STIMULATED BY THE ROBINIA PSEUDOACACIA LECTIN -- LECTINS OF ROBINIA PSEUDOACACIA -- SPECIFICITY OF HUMAN PLASMA FIBRONECTIN TOWARDS BIOMATERIALS -- STUDY OF THE GLYCOSYLATED POPULATIONS OF PLASMA ALPHA-1"ACID GLYCOPROTEIN IN HUMAN BREAST CANCER PATIENTS TREATED WITH TAMOXIFEN -- PHYSICO-CHEMICAL AND BIOCHEMICAL CHARACTERISTICS OF THE CON-A REACTIVE AND NON REACTIVE MOLECULAR VARIANTS OF HUMAN ALPHA-1"ACID GLYCOPROTEIN -- PART 2. BIOLOGICAL FUNCTIONS OF LECTINS -- BIOLOGICAL FONCTIONS OF LECTINS -- LOCALIZATION AND BIOSYNTHESIS OF LATHYRUS OCHRUS SEEDS LECTIN -- SURFACE AND TOTAL RECEPTORS FOR ASIALOGLYCOPROTEINS IN HEPATOCYTES FROM DIABETIC RATS -- PART 3. AFFINITY AND SPECIFICITY OF LECTINS -- LECTIN(S) - LIGAND(S) INTERACTIONS -- A COMPARATIVE STUDY OF AFFINITY CONSTANTS MEASURED BY DIFFERENT METHODS, BETWEEN PEANUT LECTIN AND SUGARS WITH GALACTOSYL MODIFIED ON C(6) OR C(l) -- EFFECT OF pH ON BINDING PROPERTIES OF PEANUT AGGLUTININ (PNA) -- USE OF LECTIN S TO EXAMINE THE MICROHETEROGENEITY OF RAT HEMOPEXIN -- AUTHOR INDEX -- SUBJECT INDEX -- Backmatter